Biopharma Pumping Solutions

Chromatography, virus filtration, tangential flow filtration (TFF) and inline blending are four of the more common unit operations that can be used in the manufacture of biopharmaceuticals.

In order to provide efficient, reliable and cost-effective processes in all of these unit operations, as well as guaranteeing the production of drugs that are suitable for human or animal consumption and administration, manufacturers must utilize a pump technology that features low-pulsation and low-shear operation even when encountering variable flow rates and pumping pressures.

A technology that meets all of those operational requirements is the Quaternary Diaphragm Pump from Quattroflow®, which also possesses the versatility to operate effectively in a fixed stainless-steel production setup, as well as in increasingly popular single-use manufacturing applications.

The Task

Moving a Fluid...

  • Cell suspension (mammalian, bacteria, yeast, algae, fungi, insect cells)
  • Cell free supernatant (e.g. monoclonal antibodies)
  • Virus suspension
  • Viral vaccines
  • Bacterial vaccines
  • Proteins from blood fractionation
  • Polymers & macromolecules

...through an apparatus...

  • Chromatography colums
  • Membrane cassettes
  • Membrane hollow fibres
  • Centrifuges
  • Filters
  • Homogenizers
  • Disposable bags

...to achieve your target.

  • Cell removal
  • Separation of the target protein
  • Concentration of the target protein
  • Buffer exchange (diafiltration)
  • Continous fermentation
  • Concentration of viruses
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Quattroflow Multi-Use Pumps

Multiple-Use Pumps

Multiple-use pumps have a vast array of options and flow rates to accommodate many biopharmaceutical applications. Whether your requirement is 1 lph (0.017 lpm) or 16,000 lph (267 lpm) your application is covered with high purity, easily cleanable, multiple use units.

Available in sizes 150, 1200, 4400, 5050, 10k, and 20k (arranged in order of flow capacity).

Single-Use Pumps

Single-Use Pumps

Single-use pumps reduce downtime between batches and are quick and easy to change. A new single-use pump chamber can be replaced and is ready for a new batch in less than one minute.

Available in sizes 150, 1200, 4400 and 5050 (arranged in order of flow capacity).

Quattroflow Accessories

Accessories

  • Control Boxes
  • Power Boxes
  • Diaphragm Sensors
  • PID Pressure Controllers
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Almatec BICOR Series

BIOCOR Series Pumps

Air-operated double diaphragm (AODD) pumps designed for sterile applications within the pharmaceutical, biotechnical and food industry.

Ideal for simple and batch transfer applications (e.g. column packing).

Available in three sizes B20, B32 and B40 to achieve max. capacities of 15.4/33/75 gpm (3.5/7.5/17 m³/h) respectively and a max. discharge pressure up to 100 psi (7 bar).