Our Solutions for Fill and Finish

PSG Biotech is proud to offer best-in-class pumps, flow sensors, meters and flow controls that are engineered to reliably and safely transfer and precisely meter critical biologic liquids handled during fill-and-finish processes.

Importance of Fill and Finish in the Pharma Industry

The fill-and-finish stage is a crucial part of the biopharmaceutical manufacturing process. It involves the precise filling of vials, syringes or other single-use containers with biologic-liquid products, followed by the finishing steps, such as sealing and labeling. This stage is vital for ensuring the efficacy, safety and sterility of the final product, making the choice of equipment and controls critically important.

Application-Specific Solutions

Fill-and-Finish Systems:
Our fill-and-finish systems are designed to handle various types of biologic liquids, including monoclonal antibodies, vaccines and therapeutic proteins. These systems ensure precise control over the filling process, enhancing the efficiency and reliability of the entire production process.

API Handling:
Accurate fill and finish is critical when handling APIs, which are the essential components of pharmaceutical products. Precise metering and filling ensure that each container receives the correct dosage of the API, which is vital for maintaining the potency and efficacy of the final product. Our solutions ensure that APIs are filled accurately and consistently, which is crucial for regulatory compliance and patient safety.

Sterile Filling:
In sterile filling processes, such as those used for injectable drugs, maintaining the sterility of the product is paramount. Our fill-and-finish systems are designed to operate in aseptic environments, ensuring that the biologic liquids are transferred and metered without contamination. This is especially important for products that are administered directly to patients, where sterility is critical.

Vial, Ampoule and Syringe Filling:
For applications involving the filling of vials and syringes, our fill-and-finish solutions provide the precision and reliability needed to ensure uniform doses. This reduces the risk of dosing errors and enhances the safety and efficacy of the final product. Our single-use Quattroflow (QF and QB) pumps are particularly well suited for these applications, offering the smooth and consistent flow rates that are essential for accurate filling.

Flexible Batch Processing:
For batch processing applications , our fill-and-finish systems offer the flexibility and precision needed to fill containers on demand. This reduces the need for large intermediate storage tanks and simplifies the overall production process. The ability to fill in real time also enhances process efficiency and reduces the risk of contamination.