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Award-Winning BioProTT™ FlowSU System

The BioProTT™ FlowSU System – recently named a winner of the Processing magazine 2023 Breakthrough Product Award – is an innovative flow-measurement solution for single-use biopharmaceutical applications. Suitable for both upstream and downstream processes, the ultrasonic flow meter consists of a reusable transmitter and a disposable flow sensor for integration into single-use tubing assemblies.

The approach of “Ready. Connect. Flow.” is driven by the ease of integration, smart connection to a host system or pump, and reliable, highly accurate flow-measurement capabilities that feature no obstructions within the flow path while being low maintenance. Integrated air and bubble detection ability adds a further level of safety to biopharma-production processes.

Please note: Not all products are available and approved in every country. Please contact your local distributor if you have any questions.

Application

In upstream processes such as buffer and media preparation or cell cultivation, the BioProTT™ FlowSU can provide feedback to a pump or dose feeding processes.

In downstream applications such as depth filtration, tangential flow filtration, in-line buffer formulation, or chromatography, the BioProTT™ FlowSU can be used to hygienically and precisely measure the flow. The flow meter can be easily integrated inline and be combined with different pump types such as the Quattroflow® Single Use Pumps. The integrated air and bubble detection adds safety to air-sensitive applications.

Why FlowSU Ultrasonic Flow Meters Are the Best Option for Bioprocessing

Ease of Use – “Ready. Set. Flow.”

  1. Minimal Shear: Straight flow-cell design has minimal impact on sensitive cells and proteins
  2. Ease of Use: Every sensor size easily connects to a standard transmitter mount for seamless integration
  3. Bubble Detector: Visual LED alarm as well as integrable into PLC
  4. Calibration: Pre-calibrated for every sensor size, ensuring accuracy, seamless startup and adjustable calibration table for even better results
  5. Transmitter: Easy-to-mount holder profile with integrated electronics
  6. Smart Sensor: Single-use flow measurement and air-in-line detection with one sensor
  7. Size: One transmitter size scales to all tubing sizes
  8. Single Use: No regular recalibrations with SU sensor
Optimum
Choice
SumoFlo SU Magnetic SU Turbine SU SU
Ultrasonics
Digital Communication Full Circle Full Circle Full Circle Empty Circle
Bubble detection Full Circle Half Circle Empty Circle Empty Circle
Accuracy within 2% of reading Full Circle Full Circle Full Circle Full Circle
Non-conductive fluids (such as WFI) Full Circle Full Circle Full Circle Empty Circle
No moving parts with minimal shear Full Circle Full Circle Empty Circle Full Circle
User-friendly multi-calibration table Full Circle Full Circle Empty Circle Half Circle
No pressure drop Full Circle Full Circle Empty Circle Full Circle
Small footprint and holder size Half Circle Full Circle Three Quarter Circle Half Circle
Tube-size and electronics Full Circle Half Circle Half Circle One Quarter Circle
Tubing agnostic Full Circle Empty Circle Full Circle Full Circle

Full Circle

Meets all requirements

Half Circle

Meets some requirements

Empty Circle

Does not meet requirements

Three Quarter Circle

Meets most requirements

One Quarter Circle

Meets few requirements

Key Facts

  • Pressure resistant up to 5.1 bar (74 psi)
  • Straight flow path and ultrasonic transit time principle for cell and media integrity
  • 2% accuracy without individual calibration due to standardization
  • On-site adjustment feature to improve performance on-site
  • Full compatibility of all five sensor sizes (1/4‘‘, 3/8‘‘, 1/2‘‘, 3/3‘‘, 1‘‘) with one multi-use transmitter: size is automatically recognized upon connection (replace the existing one)
  • Toolless attachment of single-use sensor with special locking technology
  • USP class VI material (polycarbonate) and gamma-stable up to 50 kGy
  • Manufactured in an ISO 13485 environment and packaged under ISO 7 clean room conditions
  • Standard hose barb connections
  • Adjustable air and bubble sensitivity
  • Selectable flow averaging rate
  • Integrated web interface for configuration (password protected)

OEM Version:

  • Stainless steel panel mount transmitter
  • CE and UL certified
  • Integrated electronics and Status LED
  • PoE with no cables at the front
  • ModBus TCP Interface equal to the BioProTT™ FlowMCP

Performance

Fig. 1: In total 175 FlowSU 1/2" were tested with water at 21°C.
All sensors were within the defined specification without an individual calibration of each sensor.

Fig. 2: Comparison of the accuracy of the BioProTT™ FlowSU System 1/2" before and after gamma irradiation (50 kGy). The curves represent the mean over 25 samples tested.

Videos

Introducing BioProTT™ FlowSU System



Flow (LPM)

0.002 - 0.05

0.002

SumoFlo U08

0.005 - 0.05

0.005

QB2

0.038 - 0.38

0.038

QB25**

0.001 - 0.5

0.001

QF30

0.02 - 1.5

0.02

SumoFlo 031

0.017 - 2

0.017

BioProTT™ 1/8"

0.02 - 3

0.02

QF150

0.5 - 5

0.5

SumoFlo 062

0.1 - 6

0.1

BioProTT™ 3/16"

0.1 - 8

0.1

BioProTT™ FlowSu 1/4"

0.1 - 8

0.1

BioProTT™ 1/4"

0.9 - 9

0.9

SumoFlo 063

0.1 - 10

0.1

BioProTT™ 3/8"

0.1 - 15

0.1

BioProTT™ FlowSu 3/8"

2 - 20

2

SumoFlo 082

0.3 - 20

0.3

BioProTT™ 1/2"

0.1 - 20

0.1

BioProTT™ FlowSu 1/2"

0.1 - 20

0.1

QF1200

4 - 40

4

SumoFlo 151

0.42 - 41.67

0.42

QF2500

2.5 - 50

2.5

BioProTT™ FlowSu 3/4"

6 - 60

6

SumoFlo 152

2 - 75

2

BioProTT™ 3/4"

2.5 - 80

2.5

BioProTT™ FlowSu 1"

0.83 - 83.33

0.83

QF4400

0.83 - 83.33

0.83

QF5050

0.83 - 100

0.83

QF5K

2 - 100

2

BioProTT™ 1"

10 - 100

10

SumoFlo 153

8.33 - 166.67

8.33

QF10K

16.67 - 266.67

16.67

QF20K